At least five people have been killed in a big explosion in Pakistan's eastern city of Lahore, doctors say.

At least five people have been killed in a big explosion in Pakistan's eastern city of Lahore, doctors say.

Reports said several others had been injured in the blast which occurred near a building of a federal investigative agency.

Pakistan TV pictures showed a damaged building. Reports said a car laden with explosives had rammed into it.

Close to the country's border with India, Lahore has been hit several times by militants over the past year.

A senior police official Mohammed Irfan told the AFP news agency that the blast had taken place near Pakistan's Federal Investigation Agency building in the Model Town area in Lahore.

TV reports said some of the neighbouring buildings had also been damaged in the explosion.

There have been a number of explosions in Lahore over the past year.

Last December, two bomb blasts at a busy market killed at least 48 people and injured over 100 people

In May 2009, a bomb attack on a police building killed at least 23 people and injured 200. The nearby offices of the ISI intelligence service were also damaged in the blast.